Abstracts

Abstracts

GRAPPA develops future thought leaders by hosting an annual Trainee Symposium. Abstracts from around the world are submitted and the best are chosen to present.

The trainee symposium promotes the dissemination and discussion of research related to dermatology and rheumatology clinical, translational, and basic science proposals.

A cytokine signature from monocyte-derived macrophages predicts response to apremilast in patients with psoriatic arthritis

Background. The immune mechanisms of action remain elusive for apremilast, a PDE4-inhibitor approved for the treatment of psoriatic arthritis

Actigraphy-derived physical activity levels and circadian rhythm parameters in patients with psoriatic arthritis: relationship with disease activity, functional impairment, mood, age and BMI.

Arthralgia with risk of progression to psoriatic arthritis in a large cohort of patients: role of ultrasound.

Background: The psoriasis- to- psoriatic arthritis (PsA) transition offers a unique opportunity to identify individuals at increased risk of developing PsA and to implement preventive strategies. Objectives: To estimate...

Characterizing the Spectrum of Spinal Inflammation in Psoriatic Arthritis by in-vivo 18F-FDG Total-Body PET/CT Imaging

Difficult to treat Psoriatic arthritis: Lack of response to methotrexate and prolonged treatment breaks predict refractory disease.

Difficult to treat Psoriatic arthritis: Lack of response to methotrexate and prolonged treatment breaks predict refractory disease...

Effectiveness And Factors Associated With Minimal Disease Activity In Upadacitinib-treated Psoriatic Arthritis Patients: 24-week Results Of A Real-life Multicenter Study (UPREAL-PsA)

Psoriatic arthritis (PsA) is an immune-mediated musculoskeletal disease characterized by clinical heterogeneous manifestations...

Effectiveness of Sequential Lines of Biologic and Targeted Synthetic Drugs in Psoriatic Disease: A Systematic Review and Meta-Analysi

Evaluation of liver fibrosis in patients with psoriasis and rheumatoid arthritis treated with methotrexate using transient elastography

Genome-Guided Proteomic Analysis Identifies Biomarkers for the Progression from Psoriasis to Psoriatic Arthritis

HLA class I alleles as a predictor of retention to treatment with IL-17 antagonists in a cohort of patients with psoriatic arthritis in Newfoundland

Background: Psoriatic arthritis (PsA) is a chronic, immune-mediated disease with genetic and environmental components to pathogenesis...

Imaging morphological characterisation of the axial manifestations of psoriatic arthritis (axial PsA)

Background. Under the umbrella term spondyloarthritis whose clinical presentations are very heterogeneous, psoriatic arthritis (PsA) and axial...

Pain Mechanisms in Psoriatic Arthritis: Differentiating Inflammation Related Pain in Enthesitis Using Ultrasound, In Comparison to Functional MRI

Approximately 50% of PsA patients have persistent pain despite a well‐controlled inflammatory state, which has been attributed to non‐nociceptive pain...

Patients developing inflammatory bowel disease before spondyloarthritis manifest significantly higher rates of enthesitis: findings from a single-center real-life cohort.

nflammatory bowel diseases (IBD) and spondyloarthritis (SpA) share numerous pathogenetic mechanisms and therapeutic options (i.e. biologics targeting TNFα...

Predicting response to therapy among patients with psoriatic arthritis - results from the British Society of Rheumatology Psoriatic Arthritis Register (BSR-PsA)

Given the number of treatment options available in psoriatic arthritis (PsA), identifying predictors of treatment response might inform management plans...

Prevalence of sternal bone edema in patients with spondyloarthritis and psoriatic arthritis with axial involvement.

Spondyloarthritis (SpA) and psoriatic arthritis (PsA) are characterized by entheseal involvement. Sternal edema  is seen as an hyperintense image on magnetic...

Regulatory role of JAK signaling on Keratinocytes and synovial cells (FLS): Novel mechanisms for JAK inhibitors in Psoriatic disease

Short-term risk and long-term incidence rate of infection and malignancy with IL-23 inhibitors in adult patients with psoriasis and psoriatic arthritis: a systematic review and meta-analysis

Synovial tissue homing properties of novel monocyte subpopulations in active treatment naïve psoriatic arthritis.

The Determinants of Radiographic Progression In Early PsA: A Longitudinal Analysis of the DEPAR Real-World Cohort

Persistent inflammation in Psoriatic arthritis (PsA) is associated with radiographic damage. Despite advances in diagnosis and therapy, radiographic...

The prevalence and incidence of psoriasis and psoriatic arthritis in England from 2009-2019: an observational study using primary care data

The transcription factor Bcl11b: a new regulator of canonical and non-canonical NF-kB pathways

Background: Bcl11b, a zinc finger bi-functional transcription factor, is highly expressed in various tissues during development and differentiation...

Usefullness of low dose CT in Psoriasis and Psoriatic Arthritis patients with non-spesific axial smptoms