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ULTRASOUND – Synovitis
Category: 
  • Imaging
Order number: 10
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ULTRASOUND – Synovitis
Category: 
  • Imaging
Order number: 20
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ULTRASOUND – Synovitis
Category: 
  • Imaging
Order number: 30
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ULTRASOUND – Enthesitis
Category: 
  • Imaging
Order number: 40
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ULTRASOUND – Enthesitis
Category: 
  • Imaging
Order number: 50
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ULTRASOUND – Enthesitis
Category: 
  • Imaging
Order number: 60
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ULTRASOUND – Enthesitis
Category: 
  • Imaging
Order number: 70
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ULTRASOUND – Enthesitis
Category: 
  • Imaging
Order number: 80
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ULTRASOUND – Paratenonitis
Category: 
  • Imaging
Order number: 90
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ULTRASOUND – Paratenonitis
Category: 
  • Imaging
Order number: 100
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ULTRASOUND – Dactylitis
Category: 
  • Imaging
Order number: 110
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ULTRASOUND – Dactylitis: tenosynovitisand subcutaneous tissue inflammation
Category: 
  • Imaging
Order number: 120
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X-Rays – Destruction and new bone formation in PsA
Category: 
  • Imaging
Order number: 130
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X-Rays – Osteodestructive changes in PsA
Category: 
  • Imaging
Order number: 140
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X-Rays – Destructive changes in PsA
Category: 
  • Imaging
Order number: 150
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X-ray – Similarities and differences between ankylosing spondylitis and psoriatic arthritis in the spine
Category: 
  • Imaging
Order number: 160
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MRI – Isolated Spinal Involvement In PsA
Category: 
  • Imaging
Order number: 170
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CT – Spinal Involvement In PsA
Category: 
  • Imaging
Order number: 180
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Outline
Category: 
  • Genetics
Order number: 10
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Psoriatic disease is a highly heritable complex genetic disease
Category: 
  • Genetics
Order number: 20
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Heritability estimates of PsV/PsC and PsA vary depending on how it is determined
Category: 
  • Genetics
Order number: 30
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Family history of Psoriasis (PsO) and PsA impacts disease severity, skin and musculoskeletal phenotypes of the proband 
Category: 
  • Genetics
Order number: 40
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Genetics 
Category: 
  • Genetics
Order number: 50
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Genome wide significant loci in PsO (recent variants reaching GWA significance are highlighted in red) 
Category: 
  • Genetics
Order number: 60
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Genome wide significant loci in PsA(recent variants reaching GWA significance are highlighted in red) 
Category: 
  • Genetics
Order number: 70
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Genes identified in psoriatic disease exhibit low genotype relative risk, so most genes do not provide clinically actionable outcomes   
Category: 
  • Genetics
Order number: 80
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HLA associations provide the most robust genetic associations in psoriatic disease  
Category: 
  • Genetics
Order number: 90
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PSORS1 and Psoriatic Disease 
Category: 
  • Genetics
Order number: 100
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HLA-Allele C*06:02 and Disease Expression in Psoriatic Disease
Category: 
  • Genetics
Order number: 110
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HLA-B associations in PsO and PsA 
Category: 
  • Genetics
Order number: 120
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Genotype-Phenotype correlations of HLA-B in PsA: HLA-Allele B*27
Category: 
  • Genetics
Order number: 130
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Genotype-Phenotype correlations of HLA-B in PsA: HLA-Allele B*08
Category: 
  • Genetics
Order number: 140
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Most of the disease susceptibility genes identified in psoriatic disease through  GWA studies are located outside the MHC region 
Category: 
  • Genetics
Order number: 150
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Susceptibility genes identified to date in psoriatic disease can be broadly categorized into several (sometimes overlapping) categories 
Category: 
  • Genetics
Order number: 160
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 Susceptibility genes and potential pathways (1 of 3) 
Category: 
  • Genetics
Order number: 170
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Susceptibility genes and potential pathways (2 of 3) 
Category: 
  • Genetics
Order number: 180
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Susceptibility genes and potential pathways (3 of 3)
Category: 
  • Genetics
Order number: 190
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Psoriatic susceptibility genes can also potentially be linked to pathways interrogated by therapeutic agents such as the IL23/IL17 pathway
Category: 
  • Genetics
Order number: 200
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Exome studies have also identified monogenic models of psoriatic disease
Category: 
  • Genetics
Order number: 210
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Proposed Model of Psoriasis Pathogenesis in the Presence of Psoriasis-Specific CARD14 Alterations
Category: 
  • Genetics
Order number: 220
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IL-36 and Pustular Psoriasis
Category: 
  • Genetics
Order number: 230
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Pharmacogenetics
Category: 
  • Genetics
Order number: 240
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Genetic variants might influence response to therapy in psoriasis
Category: 
  • Genetics
Order number: 250
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Genetic variants might influence response to therapy in psoriatic arthritis
Category: 
  • Genetics
Order number: 260
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What is there to do and research about?
Category: 
  • Genetics
Order number: 270
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Introduction to the GRAPPA Slide Library

Welcome to the GRAPPA slide library, where we have carefully curated slides to provide a comprehensive overview of psoriatic diseases. Our aim is to ensure widespread use of these slides for educating healthcare professionals involved in the care of patients with psoriatic diseases.

The library consists of eleven sections covering the following topics:

 

  1. Genetics
  2. Pathogenesis & Tissues
  3. Classification, Epidemiology, and Prognosis
  4. Clinical Features
  5. Imaging
  6. Psoriatic Skin Disease
  7. Psoriatic Nail Disease
  8. Psoriasis Treatment
  9. Psoriatic Arthritis Treatment
  10. Outcome Measures
  11. Comorbidities

Currently, all slides in the library are accessible in English and can be conveniently accessed using search terms such as keywords or by browsing the specific categories mentioned above. The slides are designed to be used as they are and should not be modified in any way. While we have taken great care to ensure the accuracy of the slide content, please note that GRAPPA cannot be held legally responsible for any potential mistakes that may have occurred.

We extend our gratitude to the GRAPPA members who contributed to the collection, selection, and editing of the slides for this library:

Genetics: Proton Rahman, Mona Stahle, and Sebastián Herrera

Pathogenesis & Tissues: Chris Ritchlin, Kurt de Vlam, Luis Puig, and Hanna Johnsson

Classification, Epidemiology, & Tissues: Philip Helliwell, Vinod Chandran, Laura Savage, Pamela Diaz, and Francesco Bellinato

Clinical Features: Dafna Gladman, Amit Garg, and Anand Kumthekar

Imaging: Lihi Eder, Denis Poddubnyy, Ummugulsum Gazel, and Cristina Macía

Treatment: Arthur Kavanaugh, Philip Mease, Laura Ferris, Joseph Merola, André Ribeiro, Betul Macit, Guilherme Muzy, and Ólafur Pálsson

Outcome Measures: Laura Coates, Kristina Callis Duffin, and Tania Gudu

Skin: Wolf-Henning Boehncke and Giovanni Damiani

Nails: Kristina Callis Duffin and Dimitri Luz

Comorbidities: Elaine Husni, Paolo Gisondi, Deepak Jadon, Jason Hawkes, Silvia Scriffignano, Barbara Hernandez, and Estella Chen

 

We also thank the authors and journals who granted us permission to use previously published figures, as indicated on the slides.

The layout and technical aspects of the slides were expertly handled by LP Concept GmbH, Germany.

The project coordination was carried out by the GRAPPA Education Committee, with supervision and coordination provided by Philip Helliwell, Fabian Proft, and Gizem Ayan. Janine Kowack and Annie Spangler provided invaluable logistical support.

Your Group for Research and Assessment of Psoriasis and Psoriatic Arthritis