Correlation among gender, genital psoriasis and sexual function in patients with psoriasis and psoriatic arthritis
Authors
Henriette Käding
Charité-Universitätsmedizin Berlin
Susanne Lüders
Charité - Universitätsmedizin Berlin
Mikhail Protopopov
Charité - Universitätsmedizin Berlin
Judith Rademacher
Charité - Universitätsmedizin Berlin
Valeria Rios Rodriguez
Charité - Universitätsmedizin Berlin
Laura Spiller
Charité - Universitätsmedizin Berlin
Murat Torgutalp
Charité - Universitätsmedizin Berlin
Denis Poddubnyy
Charité - Universitätsmedizin Berlin, Rheumatism Research Centre, Epidemiology Unit
Fabian Proft
Charité - Universitätsmedizin Berlin
Keywords
axial psoriatic arthritis; axial spondyloarthritis
INTRODUCTION
Psoriasis is a multisystem, inflammatory, chronic and recurrent disease that affects the skin, genitals, nails, scalp and joints, with a significant impact on quality of life and may contribute to sexual dysfunction. The aim of this study was to correlate gender, genital psoriasis and sexual function in patients with psoriasis and psoriatic arthritis.
METHODS
Observational, analytical and cross-sectional study of 120 patients [30 men and 30 women with psoriasis (PASI) and 30 men and 30 women with psoriatic arthritis (CASPAR)] aged between 18 and 83 years, of whom 44 had genital lesions.(Table 1) The evaluation of sexual function was performed by the sexual quotient (SQ - unfavorable performance <62), the female sexual function index (FSFI - sexual dysfunction <26.5) and the International Erectile Function Index (IEFI - erectile dysfunction <26) questionnaires. The patients were accompanied at the cutaneous joint diseases sector of the university hospital. Data analysis was performed, using the chi-square test. Pearson’s correlation was performed. The significance criterion was 5%.
RESULTS
The mean score was 18.05 for IIFE; 16.78 for FSFI; 54.57 for SQ, which represents, respectively, mild to moderate erectile dysfunction, sexual dysfunction, and reduced sexual function with fair to poor performance. (Tables 2 and 3) Regarding the presence of genital lesions, the mean SQ was 55.85 against 53.82 in patients without genital lesions. There was a positive correlation between IIFE and QS. (+0.77, r=0.592) (Graphic 1) and between FSFI and QS (+0.83, r=0.688) (Graphic 2).There was no dependence relationship (p-value= 25.57%) between the variables, existence of genital lesion and cutaneous or joint disease.
DISCUSSION AND CONCLUSION
Sexual dysfunction is characterized by the lack of proper functioning of one of the phases that make up the sexual cycle. More than 63% of patients present with a psoriasis lesion in the genital region at some stage of life. Several studies report the negative impact of psoriasis on sexual function in both sexes with frequencies ranging from 22.6% to 71.3%. The effect of psoriatic disease on sexual health may be linked to several factors. This study confirmed sexual dysfunction in patients with psoriasis or psoriatic arthritis, regardless of gender. However, the presence of genital lesions did not correlate with the degree of sexual dysfunction.